Phospho-JAK2 (Y1007 + Y1008) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-JAK2 (Y1007 + Y1008)
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentrationn/a
ApplicationsImmunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB)
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DescriptionNon-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type II receptors including IFN-alpha, IFN-beta, IFN-gamma and multiple interleukins. Following ligand-binding to cell surface receptors, phosphorylates specific tyrosine residues on the cytoplasmic tails of the receptor, creating docking sites for STATs proteins. Subsequently, phosphorylates the STATs proteins once they ar
ImmunogenImmunogen: A synthesized peptide derived from human Phospho-JAK2 (Y1007 Y1008) Subcellular Localization: Endomembrane system; Peripheral membrane protein. Cytoplasm. Nucleus. Tissue Specificity: Ubiquitously expressed throughout most tissues.
Other Names[Tyrosine-protein kinase JAK2; 2.7.10.2; Janus kinase 2; JAK-2; JAK2]
Gene, Accession #[JAK2], Gene ID: 3717, NCBI: NP_001309123.1, UniProt: O60674
Catalog #MBS1750195
Price$280
Order / More InfoPhospho-JAK2 (Y1007 + Y1008) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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