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Antigenic Specificity | Phospho-JAK2 (Y1007 + Y1008) |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type II receptors including IFN-alpha, IFN-beta, IFN-gamma and multiple interleukins. Following ligand-binding to cell surface receptors, phosphorylates specific tyrosine residues on the cytoplasmic tails of the receptor, creating docking sites for STATs proteins. Subsequently, phosphorylates the STATs proteins once they ar |
Immunogen | Immunogen: A synthesized peptide derived from human Phospho-JAK2 (Y1007 Y1008) Subcellular Localization: Endomembrane system; Peripheral membrane protein. Cytoplasm. Nucleus. Tissue Specificity: Ubiquitously expressed throughout most tissues. |
Other Names | [Tyrosine-protein kinase JAK2; 2.7.10.2; Janus kinase 2; JAK-2; JAK2] |
Gene, Accession # | [JAK2], Gene ID: 3717, NCBI: NP_001309123.1, UniProt: O60674 |
Catalog # | MBS1750195 |
Price | $280 |
Order / More Info | Phospho-JAK2 (Y1007 + Y1008) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |