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Antigenic Specificity | ATG12 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 500 ug/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR through phosphorylation of autophagy protein APG1. ATG12, another member of the autophagy protein family, forms a conjugate with ATG5; this conjugate has a ubiquitin-protein ligase -like activity for protein lipidation in autophagy. This conjugate also associates with innate immune response proteins such as RIG-I and VISA, inhibiting type I interferon production and permitting v |
Immunogen | Immunogen: ATG12 antibody was raised in Rabbit using synthetic peptide surrounding amino acid 21 of mouse APG12 as the immunogen. |
Other Names | [Rabbit ATG12; ATG12; ATG12; ATG12; HAPG12; ATG 12; ATG-12; APG12; ATG 12; APG12L; ATG-12] |
Gene, Accession # | [ATG12], Gene ID: 9140 |
Catalog # | MBS5311539 |
Price | $430 |
Order / More Info | ATG12 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |