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Antigenic Specificity | Mouse TLR6 (N-term), 1-30 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse TLR6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse TLR6. TLR6, a Type I membrane protein that belongs to the Toll-like rceptor family, participates in the innate immune response to Gram-positive bacteria and fungi. It acts via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. The protein recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. It binds to TLR2 via their respective extracellular domains, and to MyD88 vi |
Immunogen | n/a |
Other Names | [Toll-like receptor 6; CD286; Tlr6] |
Gene, Accession # | [Tlr6], Gene ID: 21899, NCBI: NP_035734.3, UniProt: Q9EPW9 |
Catalog # | MBS9205577 |
Price | $165, $370 |
Order / More Info | Mouse TLR6 (N-term), 1-30 Antibody from MYBIOSOURCE INC. |
Product Specific References | Ozinsky, A., et al., Proc. Natl. Acad. Sci. U.S.A. 97(25):13766-13771 (2000). Takeuchi, O., et al., Gene 231 (1-2), 59-65 (1999). |