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Antigenic Specificity | Bad |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Bad Antibody detects endogenous levels of total Bad. Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways. |
Immunogen | Immunogen: A synthesized peptide derived from human Bad |
Other Names | [BAD; BBC6; BCL2L8; Bcl- XL/Bcl-2 associated death promoter; Bcl-2 binding component 6; Bcl-2-like 8 protein; Bcl-xL/Bcl-2 associated death promoter] |
Gene, Accession # | [Bad], Gene ID: 572, NCBI: NP_004313.1, UniProt: Q92934 |
Catalog # | MBS4750141 |
Price | $335 |
Order / More Info | Bad Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |