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Antigenic Specificity | Phospho-PSD95 (Tyr609) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, zebrafish, bovine, horse, sheep, rabbit |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-PSD95 (Tyr609) Antibody detects endogenous levels of PSD95 only when phosphorylated at Tyr609. Description: Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. Also regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synapt |
Immunogen | Immunogen: A synthesized peptide derived from human PSD95 around the phosphorylation site of Tyr609. Tissue Specificity: Brain. |
Other Names | [Discs large homolog 4; Disks large homolog 4; DLG 4; Dlg4; DLG4_HUMAN; FLJ97752; FLJ98574; Human post synaptic density protein 95; Post synaptic density protein 95; Postsynaptic density protein 95; PSD 95; PSD-95; PSD95; SAP 90; SAP-90; SAP90; Synapse associated protein 90; Synapse-associated protein 90; Tax interaction protein 15] |
Gene, Accession # | [PSD95], Gene ID: 1742, NCBI: NP_001122299.1, UniProt: P78352 |
Catalog # | MBS9610700 |
Price | $225, $280, $340 |
Order / More Info | Phospho-PSD95 (Tyr609) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |