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Antigenic Specificity | ErbB 3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Receptor tyrosine-protein kinase erbB-3(ERBB3) detection. Tested with WB in Human. Background: ERBB3(V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3) also known as ONCOGENE ERBB3 or HER3, is an enzyme that in humans is encoded by the ERBB3 gene. This gene encodes a member of the epidermal growth factor receptor(EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. By in situ hybridization, Kraus et al.(1989) mapped the ERBB3 gene to chromosome 12q13. Carraway et al.(1994) demonstrated that ERBB3 is a receptor for heregulin and is capable of mediating HGL-stimulated tyrosine phosphorylation of itse |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human ErbB 3 (162-181aa DWRDIVRDRDAEIVVKDNGR). |
Other Names | [Receptor tyrosine-protein kinase erbB-3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3(avian); c erbB 3; c erbB3; ERBB3; ERBB3 protein; erbB3 S; ERBB3_HUMAN; Glial growth factor receptor; HER 3; HER3; LCCS2; MDA BF 1; MGC88033; p180 ErbB3; p45 sErbB3; p85 sErbB3; proto-oncogene-like protein c ErbB 3; proto-oncogene-like protein c ErbB3; Proto-oncogene-like protein c-ErbB-3; receptor tyrosine protein kinase ERB3[precursor]; Receptor tyrosine protein kinase erbB 3; Receptor tyrosine protein kinase erbB3; Receptor tyrosine-protein kinase erbB-3; Tyrosine kinase type cell surface receptor HER3; Tyrosine kinase-type cell surface receptor HER3; V erb b2 avian erythroblastic leukemia viral oncogene homolog 3; v erb b2 erythroblastic leukemia viral oncogene homolog 3(avian); v erb b2 erythroblastic leukemia viral oncogene homolog 3], [ERBB3; ERBB3; HER3; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3; HER3] |
Gene, Accession # | [ERBB3], Gene ID: 2065, NCBI: P21860.1, UniProt: P21860 |
Catalog # | MBS176212 |
Price | $280 |
Order / More Info | ErbB 3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |