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Antigenic Specificity | IKAP, |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The transcription factor NF-kappa B coordinates the activation of numerous genes in response to pathogens and pro-inflammatory cytokines, and is, therefore, vital in the development of acute and chronic inflammatory diseases. NF-kappa B is activated by cytokine-activated IKB kinases (IKKs); IKK-alpha and IKK-beta isozymes are found in large complexes. Theses large, interleukin-1-inducible IKK complexes have been found to contain a new protein, termed IKK-complex-associated protein (IKAP), which can bind NIK and IKKs and assemble them into an active kinase complex. IKAP is a scaffold protein and a regulator for 3 different kinases involved in pro-inflammatory cytokine signaling. |
Immunogen | Immunogen: C terminus of IKAP |
Other Names | [IkappaB kinase complex associated protein; Elongator complex protein 1; elongator complex protein 1; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein; IkappaB kinase complex-associated protein; IKK complex-associated protein; p150], [IKBKAP; IKBKAP; FD; DYS; ELP1; IKAP; IKI3; TOT1; ELP1; IKAP; ELP1; IKK complex-associated protein] |
Gene, Accession # | [IKAP], Gene ID: 8518, NCBI: AAC64258.1 |
Catalog # | MBS555267 |
Price | $350 |
Order / More Info | IKAP, Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |