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Antigenic Specificity | AZI2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total AZI2 protein. Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1.Fujita F., Mol. Cell. Biol. 23:7780-7793(2003).Ota T., Nat. Genet. 36:40-45(2004).Sasai M., J. Immunol. 174:27-30(2005). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from N-terminal of human AZI2. |
Other Names | [5-azacytidine-induced protein 2; NF-kappa-B-activating kinase-associated protein 1; Nak-associated protein 1; TILP; AZI2] |
Gene, Accession # | [AZI2], Gene ID: 64343, NCBI: NP_001127904.1, UniProt: Q9H6S1 |
Catalog # | MBS9404064 |
Price | $200, $255 |
Order / More Info | AZI2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |