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Antigenic Specificity | HTR3B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: HTR3B antibody detects endogenous levels of total HTR3B. Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.Subunit Structure: Forms a pentaheteromeric complex with HTR3A. Not functional as a homomeric complex.Post-translational Modifications: N-glycosylation required for membrane localization.Similarity: Belongs to the ligand-gated ion channel (TC 1.A.9) family. 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily. H |
Immunogen | Immunogen: A synthesized peptide derived from human HTR3B Subcellular Location: Cell Membrane. Presumably retained within the endoplasmic reticulum unless complexed with HTR3A. Tissue Specificity: Expressed in the brain cortex, in the caudate nucleus, the hyppocampus, the thalamus and the amygdala. Detected in the kidney and testis as well as in monocytes of the spleen, small and large intestine, uterus, prostate, ovary and placenta. |
Other Names | [5 HT3 B; 5 HT3B; 5 HTR3B; 5 hydroxytryptamine 3 receptor B subunit; 5 hydroxytryptamine receptor 3B; 5 hydroxytryptamine serotonin receptor 3B; 5-HT3-B; 5-HT3B; 5-hydroxytryptamine receptor 3B; 5HT3B_HUMAN; 5HTR3B; Htr3b; Serotonin gated ion channel subunit; Serotonin receptor 3B] |
Gene, Accession # | [HTR3B], Gene ID: 9177, NCBI: NP_006019.1, UniProt: O95264 |
Catalog # | MBS9603053 |
Price | $240, $280 |
Order / More Info | HTR3B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |