RING1 (C-term) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RING1 (C-term) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat (predicted reactivity: mouse) |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This RING1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 279-313 amino acids from the C-terminal region of human RING1. Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chro |
| Immunogen | n/a |
| Other Names | [E3 ubiquitin-protein ligase RING1; 632-; Polycomb complex protein RING1; RING finger protein 1; Really interesting new gene 1 protein; RING1; RNF1] |
| Gene, Accession # | [RING1], Gene ID: 6015, NCBI: NP_002922.2, UniProt: Q06587 |
| Catalog # | MBS9208849 |
| Price | $165, $370 |
| Order / More Info | RING1 (C-term) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Lovering R.,et al.Proc. Natl. Acad. Sci. U.S.A. 90:2112-2116(1993). Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004). Mungall A.J.,et al.Nature 425:805-811(2003). Satijn D.P.E.,et al.Mol. Cell. Biol. 17:4105-4113(1997). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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