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Antigenic Specificity | PIP5K |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PIP5K antibody detects endogenous levels of total PIP5K. Function: The PI(3, 5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3, 5-bisphosphate (PtdIns(3, 5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3, 5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. Plays a role in the biogenesis of endosome carrier vesicles (ECV)/multivesicular bodies (MVB) transport intermediates from early endosomes.Subunit Structure: Component of the PI(3, 5)P2 regulatory complex/PAS complex, at least composed of PIKFYVE, FIG4 and VAC14. VAC14 nucleates the assembly of the compl |
Immunogen | Immunogen: A synthesized peptide derived from human PIP5K Subcellular Location: Endosome Membrane. Mainly associated with membranes of the late endocytic pathway. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken Similarity: Pig (100%), Zebrafish (88%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (89%) |
Other Names | [1 phosphatidylinositol 3 phosphate 5 kinase; 1 phosphatidylinositol 4 phosphate 5 kinase; 1-phosphatidylinositol 3-phosphate 5-kinase; CFD; epididymis luminal protein 37; FAB1; FAB1, S. cerevisiae, homolog of; FYV1_HUMAN; FYVE finger containing phosphoinositide kinase; FYVE finger-containing phosphoinositide kinase; KIAA0981; MGC40423; p235; Phosphatidylinositol 3 phosphate 5 kinase type III; Phosphatidylinositol 3 phosphate/phosphatidylinositol 5 kinase type III; Phosphatidylinositol 3-phosphate 5-kinase; Phosphatidylinositol 3-phosphate 5-kinase type III; Phosphatidylinositol 4 phosphate 5 kinase type III; Phosphoinositide kinase, FYVE finger containing; PIKfyve; PIP5K; PIP5K3; PIPkin III; PIPkin-III; PtdIns(4)P 5 kinase; Type III PIP kinase; ZFYVE29; Zinc finger, FYVE domain containing 29] |
Gene, Accession # | [PIP5K], Gene ID: 200576, NCBI: NP_001171471.1, UniProt: Q9Y2I7 |
Catalog # | MBS9609024 |
Price | $240, $280 |
Order / More Info | PIP5K Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |