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Antigenic Specificity | Amyloid Beta Peptide 42 |
Clone | [CA9 3F8] |
Host Species | Mouse |
Reactive Species | human and other primates; mouse and rat. |
Isotype | IgG2b,k |
Format | Protein G purified |
Size | 0.5 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes the C-terminal sequence (MVGGVVIA) of Aβ42 and full length Aβ42. Description: Mouse monoclonal antibody to Cterminal of amyloid beta peptide 42 (Abeta42) Background: Amyloid beta peptide 42 (Abeta42) is best known for its role in the formation of senile plaques in the brain of patients with Alzheimer's disease. Abeta42 and Abeta40 are the two major amyloid peptides that are produced after cleavage of amyloid precursor protein by secretases. Abeta42 (42 amino acids) is very fibrillogenic. The beta pleated structure of Abeta42 constituents the initial and key component of the insoluble amyloid fibril in senile plaque. It is widely accepted that Abeta42 contributes to the pathogenesis of Alzheimer's disease. |
Immunogen | Immunogen: KLH conjugated to a short peptide (MVGGVVIA) with amino acid sequence corresponding to the C terminal of Aβ42 Target Protein: C-terminal of amyloid beta peptide 42 |
Other Names | n/a |
Gene, Accession # | [Ab42] |
Catalog # | MBS592412 |
Price | $445 |
Order / More Info | Amyloid Beta Peptide 42 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |