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Antigenic Specificity | H-NUC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total H-NUC protein. Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.Tugendreich S., Proc. Natl. Acad. Sci. U.S.A. 90:10031-10035(1993).Chen P.L., Cell Growth Differ. 6:199-210(1995).Kraft C., EMBO J. 22:6598-6609(2003). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human H-NUC. |
Other Names | [CDC27Hs; Cell division cycle protein 27 homolog; H-NUC] |
Gene, Accession # | [H-NUC], Gene ID: 996, NCBI: NP_001107563.1, UniProt: P30260 |
Catalog # | MBS9405062 |
Price | $200, $255 |
Order / More Info | H-NUC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |