H-NUC Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityH-NUC
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous levels of total H-NUC protein. Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.Tugendreich S., Proc. Natl. Acad. Sci. U.S.A. 90:10031-10035(1993).Chen P.L., Cell Growth Differ. 6:199-210(1995).Kraft C., EMBO J. 22:6598-6609(2003).
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human H-NUC.
Other Names[CDC27Hs; Cell division cycle protein 27 homolog; H-NUC]
Gene, Accession #[H-NUC], Gene ID: 996, NCBI: NP_001107563.1, UniProt: P30260
Catalog #MBS9405062
Price$200, $255
Order / More InfoH-NUC Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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