Human Caspase-3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Caspase-3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatcaprylic acid ammonium sulfate precipitate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionInvolved in the activation cascade of caspases responsible for apoptosis execution.This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer s disea
ImmunogenImmunogen: Recombinant human Caspase-3 protein
Other Names[Apopain; Cysteine protease CPP32Protein Yama; SREBP cleavage activity 1]
Gene, Accession #[CASP3], Gene ID: 836, NCBI: NP_004337.2, UniProt: P42574
Catalog #MBS7001270
Price$160, $235
Order / More InfoHuman Caspase-3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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