MGEA5 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMGEA5
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration0.6 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total MGEA5 protein. The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT, which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications. Cleaves GlcNAc but not GalNAc from glycopeptides. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc. Possesses hyaluronidase activity. Acetylates 'Lys-8' of histone H4 and 'Lys-14' of histone H3. Shows highest expression in the brain, placenta and pancreas.
ImmunogenImmunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to a region derived from internal residues of human Meningioma expressed antigen 5 (hyaluronidase)
Other Names[OGA; MEA5; NCOAT]
Gene, Accession #[MGEA5], Gene ID: 10724, NCBI: NP_001135906.1, UniProt: O60502
Catalog #MBS9402553
Price$255
Order / More InfoMGEA5 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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