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Antigenic Specificity | Caspase-3(P10) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Caspase-3(CASP3) detection. Tested with WB, IHC-P, ICC in Human. Background: Caspase 3 is a caspase protein which interacts with Survivin, XIAP, CFLAR, Caspase 8, HCLS1, Deleted in Colorectal Cancer, TRAF3 and GroEL. This gene which is located at 4q35 encodes a protein that is a member of the cysteine-aspartic acid protease(caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7, and 9; and the protein i |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Caspase-3 (P10) (220-236aa CAMLKQYADKLEFMHIL). |
Other Names | [Caspase-3(CASP-3); caspase 3, apoptosis-related cysteine peptidase; A830040C14Rik; Apopain; Apopain precursor; CASP 3; CASP-3; CASP3; Casp3a; Caspase 3; Caspase 3 apoptosis related cysteine protease; Caspase 3 p12 subunit; Caspase 3, apoptosis-related cysteine peptidase; Caspase 3, apoptosis-related cysteine protease; Caspase 3, apoptosis-related cysteine protease a; Caspase-3 subunit p12; Caspase3; CC3; CPP 32; CPP-32; CPP32; CPP32B; Cysteine protease CPP32; EC 3.4.22.56; Human cysteine protease CPP32 isoform alpha mRNA complete cds; ICE3; LICE; mldy; OTTHUMP00000165052; OTTHUMP00000165053; OTTHUMP00000165054; PARP cleavage protease; Procaspase3; Protein Yama; SCA 1; SCA-1; SCA1; SREBP cleavage activity 1; Yama; Yama protein], [CASP3; CASP3; CPP32; SCA-1; CPP32B; CPP32; CASP-3; CPP-32; SCA-1] |
Gene, Accession # | [CASP3], Gene ID: 836, NCBI: P42574.2, UniProt: P42574 |
Catalog # | MBS176271 |
Price | $315 |
Order / More Info | Caspase-3(P10) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |