CD274/PD-L1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD274/PD-L1
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman
IsotypeIgG
Formatunconjugated
Size0.02 mL, 0.05 mL, 0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Flow Cytometry (FC/FACS)
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DescriptionThis gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many typ
ImmunogenSource Note: This monoclonal antibody is produced by immunizing animals with a polypeptide corresponding to CD274/PD-L1 protein.
Other Names[Programmed cell death 1 ligand 1], [PD-L1; CD274; B7-H; B7-H1; B7H1; PDCD1LG1; PDL1]
Gene, Accession #[CD274/PD-L1], Gene ID: 29126, NCBI: NP_001254635.1, UniProt: Q9NZQ7
Catalog #MBS435219
Price$225, $350, $565
Order / More InfoCD274/PD-L1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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