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Antigenic Specificity | ADAMTS4, CT |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | Protein A purified |
Size | 0.2 mL |
Concentration | n/a |
Applications | ELISA (EL/EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human ADAMTS4 at ~90kD. ADAMTS4 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the |
Immunogen | Immunogen: KLH-conjugated synthetic peptide corresponding to a portion of amino acids within the range aa713-743 near the C-terminal region of human ADAMTS4 |
Other Names | ADAMTS4, CT (ADMP-1, Aggrecanase-1, A Disintegrin And Metalloproteinase With Thrombospondin Motifs 4, ADAMTS-4, ADAM-TS 4, ADAM-TS4, KIAA0688, UNQ769/PRO1563) |
Gene, Accession # | Gene ID: 9507, NCBI: NP_005090.3, UniProt: O75173 |
Catalog # | MBS627201 |
Price | $610 |
Order / More Info | ADAMTS4, CT Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |