ADAMTS4, CT Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityADAMTS4, CT
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
FormatProtein A purified
Size0.2 mL
Concentrationn/a
ApplicationsELISA (EL/EIA), Western Blot (WB)
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DescriptionRecognizes human ADAMTS4 at ~90kD. ADAMTS4 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the
ImmunogenImmunogen: KLH-conjugated synthetic peptide corresponding to a portion of amino acids within the range aa713-743 near the C-terminal region of human ADAMTS4
Other NamesADAMTS4, CT (ADMP-1, Aggrecanase-1, A Disintegrin And Metalloproteinase With Thrombospondin Motifs 4, ADAMTS-4, ADAM-TS 4, ADAM-TS4, KIAA0688, UNQ769/PRO1563)
Gene, Accession #Gene ID: 9507, NCBI: NP_005090.3, UniProt: O75173
Catalog #MBS627201
Price$610
Order / More InfoADAMTS4, CT Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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