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Antigenic Specificity | CASP9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9. |
Immunogen | Immunogen: Recombinant protein of human CASP9 |
Other Names | [MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6] |
Gene, Accession # | [CASP9], Gene ID: 842, NCBI: NP_001220.2, UniProt: P55211 |
Catalog # | MBS8544000 |
Price | $280 |
Order / More Info | CASP9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |