CBX5 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-CBX5 antibody, protein, ELISA kits.
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| Antigenic Specificity | CBX5 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Heterochromatin protein 1 (HP1) is a family of heterochromatic adaptor molecules involved in both gene silencing and higher order chromatin structure (1). All three HP1 family members (alpha, beta and gamma) are primarily associated with centromeric heterochromatin; however, HP1beta and gamma also localize to euchromatic sites in the genome (2,3). HP1 proteins are approximately 25 kDa in size and each contains a conserved aminoterminal chromodomain, followed by a variable hinge region and a conserved carboxyterminal chromoshadow domain. The chromodomain facilitates binding to histone H3 trimethylated on Lys9, a histone mark closely associated with centromeric heterochromatin (4,5). The variable hinge region binds both RNA and DNA in a seq |
| Immunogen | Immunogen: Fusion protein of human CBX5 |
| Other Names | [CBX5; HP1a Blocking Peptide; CBX5; HP1; HP1A], [CBX5; CBX5; HP1; HP1A; HP1A; HP1 alpha] |
| Gene, Accession # | Gene ID: 23468, NCBI: NP_001120793.1, UniProt: P45973 |
| Catalog # | MBS125471 |
| Price | $275, $430 |
| Order / More Info | CBX5 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Maison, C. and Almouzni, G. (2004) Nat. Rev. Mol. Cell Biol. 5, 296-304. 2. Minc, E. et al. (2000) Cytogenet. Cell Genet. 90, 279-284. 3. Nielsen, A.L. et al. (2001) Mol. Cell 7, 729-739. 4. Lachner, M. et al. (2001) Nature 410, 116-120. 5. Bannister, A.J. et al. (2001) Nature 410, 120-124. 6. Muchardt, C. et al. (2002) EMBO Rep. 3, 975-981. 7. Yamamoto, K. and Sonoda, M. (2003) Biochem. Biophys. Res. Commun. 301, 287-292. 8. Fuks, F. et al. (2003) Nucleic Acids Res. 31, 2305-2312. 9. Murzina, N. et al. (1999) Mol. Cell 4, 529-540. 10. Nielsen, S.J. et al. (2001) Nature 412, 561-565. 11. Ogawa, H. et al. (2002) Science 296, 1132-1136. 12. Minc, E. et al. (1999) Chromosoma 108, 220-234. 13. Zhao, T. et al. (2001) J. Biol. Chem. 276, 9512-9518. 14. Lomberk, G. et al. (2006) Nat. Cell Biol. 8, 407-415. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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