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Antigenic Specificity | ZO-1, Human |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | dog, mouse |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | 100 ug/ml |
Applications | Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The polyclonal antibody recognizes human zona occludens 1 (ZO-1), an ~220 kDa tight junction protein belonging to the membrane-associated guanlyate kinase (MAGUK) family. Members of this family are involved in epithelial and endothelial intercellular junctions. They each contain at least one PSD95/Dlg/ZO-1 (PDZ) domain, a Src homology 3 (SH3) domain, and an enzymatically inactive guanylate kinase domain. PDZ domains are 90-amino acid protein-protein binding domains that recognize at least a 3-residue peptide motif in the COOH termini of their binding partners. PDZ domain-containing proteins, like ZO-1, typically act as scaffolding proteins that organize membrane receptors and cytosolic proteins into multimeric signaling complexes often at t |
Immunogen | Immunogen: Recombinant human GST-ZO-1 (aa 1-888) |
Other Names | [Tight junction protein 1 (TJP1)], [Tjp1; Tjp1; ZO1; Zo1] |
Gene, Accession # | [ZO-1], Gene ID: 21872, NCBI: BAA03274.1 |
Catalog # | MBS584518 |
Price | $555 |
Order / More Info | ZO-1, Human Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |