ADAMTS-4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityADAMTS-4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentration1ug/ul
ApplicationsWestern Blot (WB)
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DescriptionDescription: The antibody is a polyclonal antibody made to the metalloproteinase ADAMTS-4. The antibody is made to a synthetic peptide based on the propeptide domain of human ADAMTS-4. The antibody has been peptide-affinity purified, concentrated to 1 mg/ml, with the addition of 0.05% Sodium Azide as preservative and 50% glycerol as cryoprotectant. ADAMTS-4, also known as aggrecanase-1, was first described as a protein elevated in arthritic synovium. Initial observations indicated a role for ADAMTS-4 in aggrecan cleavage and cartilage destruction, especially in arthritis. Aggrecan, versican and brevican are all cleaved by ADAMTS-4, and specific inhibition of ADAMTS-4 appears to block degradation of these matrix components. Induction of ADAM
ImmunogenImmunogen: Synthetic peptide based on the propeptide domain of human ADAMTS4.
Other NamesADAMTS-4 (A Disintigrin And Metalloproteinase with Thrombospondin Motif-4, Aggrecanase-1), Propeptide Domain
Gene, Accession #[ADAMTS-4]
Catalog #MBS4157484
Price$1080
Order / More InfoADAMTS-4 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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