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Antigenic Specificity | ADAMTS-4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | 1ug/ul |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: The antibody is a polyclonal antibody made to the metalloproteinase ADAMTS-4. The antibody is made to a synthetic peptide based on the propeptide domain of human ADAMTS-4. The antibody has been peptide-affinity purified, concentrated to 1 mg/ml, with the addition of 0.05% Sodium Azide as preservative and 50% glycerol as cryoprotectant. ADAMTS-4, also known as aggrecanase-1, was first described as a protein elevated in arthritic synovium. Initial observations indicated a role for ADAMTS-4 in aggrecan cleavage and cartilage destruction, especially in arthritis. Aggrecan, versican and brevican are all cleaved by ADAMTS-4, and specific inhibition of ADAMTS-4 appears to block degradation of these matrix components. Induction of ADAM |
Immunogen | Immunogen: Synthetic peptide based on the propeptide domain of human ADAMTS4. |
Other Names | ADAMTS-4 (A Disintigrin And Metalloproteinase with Thrombospondin Motif-4, Aggrecanase-1), Propeptide Domain |
Gene, Accession # | [ADAMTS-4] |
Catalog # | MBS4157484 |
Price | $1080 |
Order / More Info | ADAMTS-4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |