Mouse TIM-1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse TIM-1 |
| Clone | [RMT1-10] |
| Host Species | Rat |
| Reactive Species | n/a |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | IgG concentration 1 mg/ml |
| Applications | ELISA (EIA), Flow cytometry (FC/FACS), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rat anti Mouse TIM-1 antibody, clone MBS239187-10 recognizes mouse Tim-1 (T-cell immunoglobulin mucin 1), a cell surface glycoprotein and member of the immunoglobulin superfamily, which was first identified as the hepatitis A virus cellular receptor (HAVCR), and is highly expressed in the liver (isoform Tim-1a) and the kidneys (isoform Tim-1b). Tim-1 is highly expressed by activated CD4+ T cells, and acts as a positive/negative co-stimulatory molecule of T cell proliferation, cytokine production and tolerance abrogation, and is the receptor for Tim-4, expressed on APCs. Tim-1 expression is greater on Th2 than Th1 cells, and studies have shown that interaction between Tim-1 on Th2 cells and Tim-4 on dendritic cells (DCs), enhances Th2 cell f |
| Immunogen | Immunogen: Full-length mouse Tim-1-Ig, containing both the IgV and mucin domains of Tim-1. Fusion Partners: Lymph node cells from immunised SD rats were fused with cells of the P3U1 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Mouse |
| Other Names | [hepatitis A virus cellular receptor 1 homolog isoform b; Hepatitis A virus cellular receptor 1 homolog; hepatitis A virus cellular receptor 1 homolog; HAVcr-1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin mucin receptor 1; TIMD-1; kidney injury molecule 1; t cell immunoglobulin and mucin domain-containing protein 1; t cell membrane protein 1; hepatitis A virus cellular receptor 1; Kidney injury molecule 1; KIM-1; T cell immunoglobulin and mucin domain-containing protein 1; TIMD-1; T cell membrane protein 1; T-cell immunoglobulin mucin receptor 1; TIM-1], [Havcr1; Havcr1; Tim1; KIM-1; TIM-1; Timd1; AI503787; Kim1; Tim1; Timd1; HAVcr-1; KIM-1; TIMD-1; TIM-1] |
| Gene, Accession # | [TIM-1], Gene ID: 171283, NCBI: NP_001160103.1, UniProt: Q5QNS5 |
| Catalog # | MBS224461 |
| Price | $300 |
| Order / More Info | Mouse TIM-1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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