Human GFAP (C-TERMINAL) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman GFAP (C-TERMINAL)
Clonepolyclonal
Host SpeciesGoat
Reactive Speciesdog (expected from sequence), mouse, rat (expected from sequence)
Isotypen/a
Formatunconjugated
Size0.1 mg
ConcentrationIgG concentration 0.5mg/ml
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionThis item recognises an epitope within the C-terminal (CT) region of human GFAP (glial fibrillary acidic protein), a class III intermediate filament (IF) protein specifically expressed by glial cells or cells of glial origin e.g astrocytes, ependymal cells and Schwann cells.. GFAP plays a role in several cellular functions within the central nervous system (CNS), including cell structure and stability, communication, motility and mitosis, and is rapidly synthesized during astrogliosis, following trauma/injury. Mutations in the GFAP gene are responsible for the rare autosomal dominant disorder known as Alexander disease, resulting in the destruction of brain white matter and the formation of fibrous, eosinophilic deposits known as Rosenthal
ImmunogenImmunogen: Peptide sequence C-DGEVIKESKQEHKD from the C-terminal region of GFAP (NP 002046.1). Buffer Solution: TRIS buffered saline Antiserum Preparation: Antiserum to human GFAP (CT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. Target Species: Human
Other Names[glial fibrillary acidic protein isoform 2; Glial fibrillary acidic protein; glial fibrillary acidic protein; glial fibrillary acidic protein], [GFAP; GFAP; GFAP]
Gene, Accession #[GFAP], Gene ID: 2670, NCBI: NP_001124491.1, UniProt: P14136
Catalog #MBS222916
Price$550
Order / More InfoHuman GFAP (C-TERMINAL) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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