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Antigenic Specificity | Human GFAP (C-TERMINAL) |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | dog (expected from sequence), mouse, rat (expected from sequence) |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 0.5mg/ml |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item recognises an epitope within the C-terminal (CT) region of human GFAP (glial fibrillary acidic protein), a class III intermediate filament (IF) protein specifically expressed by glial cells or cells of glial origin e.g astrocytes, ependymal cells and Schwann cells.. GFAP plays a role in several cellular functions within the central nervous system (CNS), including cell structure and stability, communication, motility and mitosis, and is rapidly synthesized during astrogliosis, following trauma/injury. Mutations in the GFAP gene are responsible for the rare autosomal dominant disorder known as Alexander disease, resulting in the destruction of brain white matter and the formation of fibrous, eosinophilic deposits known as Rosenthal |
Immunogen | Immunogen: Peptide sequence C-DGEVIKESKQEHKD from the C-terminal region of GFAP (NP 002046.1). Buffer Solution: TRIS buffered saline Antiserum Preparation: Antiserum to human GFAP (CT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. Target Species: Human |
Other Names | [glial fibrillary acidic protein isoform 2; Glial fibrillary acidic protein; glial fibrillary acidic protein; glial fibrillary acidic protein], [GFAP; GFAP; GFAP] |
Gene, Accession # | [GFAP], Gene ID: 2670, NCBI: NP_001124491.1, UniProt: P14136 |
Catalog # | MBS222916 |
Price | $550 |
Order / More Info | Human GFAP (C-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |