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Antigenic Specificity | CCNT1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CCNT1 antibody detects endogenous levels of total CCNT1. Function: Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNA Pol II).Subunit Structure: Cyclin-T1 is the predominant cyclin that associates with CDK9 to form a heterodimer called P-TEFb. P-TEFb forms a complex with AFF4/AF5Q31. Component of a complex which is at least composed of HTATSF1/Tat-SF1, P-TEFb complex, RNA pol II, SUPT5H, and NCL/nucleolin (PubMed:10393184). Component of the 7SK snR |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus. Tissue Specificity: Ubiquitously expressed. Predicted Cross Reactivity: Bovine, Horse, Sheep, Rabbit Similarity: Bovine (100%), Horse (100%), Sheep (100%), Rabbit (89%) |
Other Names | [CCN T1; CCNT; CCNT 1; Ccnt1; CCNT1_HUMAN; CDK9 associated C type protein; Cyc T1; Cyclin C related protein; Cyclin T; cyclin T1; Cyclin T1b; Cyclin-T; Cyclin-T1; CYCT 1; CycT1; HIVE1; Human immunodeficiency virus 1 expression; Human immunodeficiency virus type 1 (HIV 1) expression (elevated) 1; pTEFb subunit; Subunit of positive elongation transcription factor b] |
Gene, Accession # | [CCNT1], Gene ID: 904, NCBI: NP_001231.2, UniProt: O60563 |
Catalog # | MBS9603821 |
Price | $240, $280 |
Order / More Info | CCNT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |