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Antigenic Specificity | RAN |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, monkey |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs. Switches between a cytoplasmic GDP-and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis. Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP-bound RAN and release them upon direct interaction with GTP-bound RAN while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment and ensure the directionality of the transport. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-216 of human RAN (NP 006316.1). |
Other Names | [TC4; Gsp1; ARA24] |
Gene, Accession # | [RAN], Gene ID: 5901, NCBI: NP_006316.1, UniProt: P62826 |
Catalog # | MBS8544151 |
Price | $280 |
Order / More Info | RAN Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |