Phospho-VAV1-Y174 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-VAV1-Y174
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration1mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been obser
ImmunogenImmunogen: A phospho specific peptide corresponding to residues surrounding Y174 of human VAV1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Namesn/a
Gene, Accession #[VAV1-Y174]
Catalog #MBS4152927
Price$510
Order / More InfoPhospho-VAV1-Y174 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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