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Antigenic Specificity | MMP9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MMP9 antibody detects endogenous levels of total MMP9. Description: May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. Belongs to the peptidase M10A family. Activated by 4-aminophenylmercuric acetate and phorbol ester. Exists as monomer or homodimer; disulfide-linked. Exists also as heterodimer with a 25 kDa protein. Macrophages and transformed cell lines produce only the monomeric form. Interacts with ECM1.Sub |
Immunogen | Immunogen: A synthesized peptide derived from human MMP9 Subcellular Location: Secreted, Extracellular Space, Extracellular Matrix. Tissue Specificity: Produced by normal alveolar macrophages and granulocytes. |
Other Names | [82 kDa matrix metalloproteinase-9; 92 kDa gelatinase; 92 kDa type IV collagenase; CLG 4B; CLG4B; Collagenase Type 4 beta; Collagenase type IV 92 KD; EC 3.4.24.35; Gelatinase 92 KD; Gelatinase B; Gelatinase beta; GelatinaseB; GELB; Macrophage gelatinase; MANDP2; Matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); Matrix Metalloproteinase 9; MMP 9; MMP-9; MMP9; MMP9_HUMAN; Type V collagenase] |
Gene, Accession # | [MMP9], Gene ID: 4318, NCBI: NP_004985.2, UniProt: P14780 |
Catalog # | MBS9600157 |
Price | $240, $280 |
Order / More Info | MMP9 Antibody from MYBIOSOURCE INC. |
Product Specific References | Kong J, Di C, Piao J, Sun J, Han L, Chen L, Yan G, Lin Z; Journal: Oncotarget. Ezrin contributes to cervical cancer progression through induction of epithelial-mesenchymal transition. |