Phospho-LCP1 (Tyr28) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-LCP1 (Tyr28) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-LCP1 (Tyr28) antibody detects endogenous levels of LCP1. Function: Actin-binding protein (PubMed:16636079, PubMed:17294403, PubMed:28493397). Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28 (PubMed:17294403). Modulates the cell surface expression of IL2RA/CD25 and CD69 (PubMed:17294403).Subunit Structure: Monomer. Interacts with AIF1 (By similarity). Interacts with actin (PubMed:28493397).Post-translational Modifications: Phosphorylated on a serine residue in response to costimulation through TCR/CD3 and CD2 or CD28. Serine phosphorylation promotes association with the actin cytoskeleton and targeting to peripheral cell projections. |
| Immunogen | Immunogen: A synthesized peptide derived from human LCP1 around the phosphorylation site of Tyr28. Subcellular Location: Cytoplasm > Cytoskeleton. Cell Junction. Cell Projection. Cell Projection > Ruffle Membrane. Relocalizes to the immunological synapse between peripheral blood T lymphocytes and antibody-presenting cells in response to costimulation through TCR/CD3 and CD2 or CD28. Associated with the actin cytoskeleton at membrane ruffles (By similarity). Relocalizes to actin-rich cell project |
| Other Names | [CP64; L plastin; L-plastin; Larval cuticle protein 1; LC64P; LCP-1; LCP1; LPL; Lplastin; Lymphocyte cytosolic protein 1; Plastin 2; Plastin-2; PLS2; PLSL_HUMAN] |
| Gene, Accession # | [LCP1], Gene ID: 3936, NCBI: NP_002289.2, UniProt: P13796 |
| Catalog # | MBS9600688 |
| Price | $240, $280 |
| Order / More Info | Phospho-LCP1 (Tyr28) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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