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Antigenic Specificity | LRP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: LRP1 Polyclonal Antibody detects endogenous levels of LRP1 protein. LRP1 encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower |
Immunogen | Immunogen: Synthesized peptide derived from human LRP1 around the non-phosphorylation site of S4520 |
Other Names | [Rabbit LRP1; LRP1; A2MR; APR; Prolow-density lipoprotein receptor-related protein 1; LRP-1; Alpha-2-macroglobulin receptor; A2MR; Apolipoprotein E receptor; APOER; CD antigen CD91] |
Gene, Accession # | [LRP1], Gene ID: 4035, NCBI: NP_002323.2, UniProt: Q07954 |
Catalog # | MBS9705774 |
Price | $130, $220, $325 |
Order / More Info | LRP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |