Edit |   |
---|---|
Antigenic Specificity | SHAN3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of SHAN3 protein. SHANK3 is a member of the Shank gene family. Shank proteins are multidomain scaffold proteins of the postsynaptic density that connect neurotransmitter receptors, ion channels, and other membrane proteins to the actin cytoskeleton and G-protein-coupled signaling pathways. Shank proteins also play a role in synapse formation and dendritic spine maturation. Mutations in SHANK3 are a cause of autism spectrum disorder (ASD), which is characterized by impairments in social interaction and communication, and restricted behavioral patterns and interests. Mutations in SHANK3 also cause schizophrenia type 15, and are a major causative factor in the neurological symptoms of 22q13.3 deletion syn |
Immunogen | Immunogen: Synthesized peptide derived from part region of human SHAN3 protein |
Other Names | [Rabbit SHAN3; SH3 and multiple ankyrin repeat domains protein 3; Shank3; Proline-rich synapse-associated protein 2; ProSAP2] |
Gene, Accession # | [SHAN3], Gene ID: 85358, NCBI: NP_001073889, UniProt: Q9BYB0 |
Catalog # | MBS9710928 |
Price | $130, $220, $325 |
Order / More Info | SHAN3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |