MIS Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMIS
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThe antibody detects endogenous levels of MIS protein. AMH encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig c
ImmunogenImmunogen: Synthesized peptide derived from part region of human MIS protein at amino acid sequence of 380-460
Other Names[Rabbit MIS; Muellerian hormone; AMH; Muellerian-inhibiting substance; MIS]
Gene, Accession #[MIS], Gene ID: 268, NCBI: NP_000470.2, UniProt: P03971
Catalog #MBS9709836
Price$130, $220, $325
Order / More InfoMIS Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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