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Antigenic Specificity | PC2 (CBX4) (N-term), 80-110 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PC2 (CBX4) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-110 amino acids from the N-terminal region of human PC2 (CBX4). CBX4 is a member of Drosophila Polycomb group gene family. The polycomb group (PcG) genes are essential for maintenance of proper expression patterns of developmental master regulators; changes in expression pf PcG proteins have been associated with cancer. CBX4 is a part of the cellular memory system responsible for the inheritance of gene activity by progeny cells. It participates in maintaining the transcriptionally repressive state of genes. CBX4 is part of acomplex that acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of |
Immunogen | n/a |
Other Names | [E3 SUMO-protein ligase CBX4; 632-; Chromobox protein homolog 4; Polycomb 2 homolog; Pc2; hPc2; CBX4] |
Gene, Accession # | [CBX4], Gene ID: 8535, NCBI: NP_003646.2, UniProt: O00257 |
Catalog # | MBS9207298 |
Price | $165, $370 |
Order / More Info | PC2 (CBX4) (N-term), 80-110 Antibody from MYBIOSOURCE INC. |
Product Specific References | Kagey, M.H., et al., Cell 113(1):127-137 (2003). Satijn, D.P., et al., Mol. Cell. Biol. 17(10):6076-6086 (1997). |