Edit |   |
---|---|
Antigenic Specificity | CDC37 |
Clone | [AT3G7] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, k |
Format | Protein A purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1 mg/ml |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is highly similar to CDC37, a cell division cycle control protein of Saccharomyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF1, MOK, as well as eIF-2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. |
Immunogen | Immunogen: Recombinant human CDC37 (1-378aa) purified from E. coli |
Other Names | [Cell division cycle 37 homolog; P50CDC37; CDC37; Cell division cycle 37 homolog; Cell division cycle 37 homolog S cerevisiae hypothetical protein CDC37; CDC 37; CDC37 cell division cycle 37 homolog; Cdc37 homolog; CDC37 protein; Hsp90 chaperone protein kinase targeting subunit; Hsp90 chaperone protein kinase targeting subunit p50Cdc37; Hsp90 co chaperone Cdc37; p50; p50Cdc37.], [CDC37; CDC37; P50CDC37; CDC37A] |
Gene, Accession # | [CDC37], Gene ID: 11140, NCBI: NP_008996, UniProt: Q16543 |
Catalog # | MBS200434 |
Price | $240, $315 |
Order / More Info | CDC37 Antibody from MYBIOSOURCE INC. |
Product Specific References | Quotti Tubi, et al. (2013) J Hematol Oncol. 6: 78.; Manni S., et al. (2012) Clin Cancer Res. 18: 1888-900. |