CTLA4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCTLA4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatProtein A purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB); Immunohistochemistry (IHC) Paraffin
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DescriptionRabbit polyclonal unconjugated antibody to detect CTLA4 in human samples. CTLA4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain; a transmembrane domain; and a cytoplasmic tail. Alternate transcriptional splice variants; encoding different isoforms; have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond; while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus; Graves disease; Hashimoto thyroiditis; celiac disease; systemic lupus erythematosus; thyroid-associated orbitopathy; and other autoimmune diseases.
ImmunogenImmunogen: KLH conjugated synthetic peptide between 50-78 amino acids from the N-terminal region of human IDDM12.
Other Names[Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4; CD152; CTLA4; CD152], [CTLA4; CTLA4; CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3; CD152; CTLA-4]
Gene, Accession #[CTLA4], Gene ID: 1493, NCBI: NP_001032720.1, UniProt: P16410
Catalog #MBS845961
Price$210
Order / More InfoCTLA4 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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