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Antigenic Specificity | TNFRSF10A (C-term), 418-446 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.43 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This TNFRSF10A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 418-446 amino acids from the C-terminal region of human TNFRSF10A. The protein encoded by this gene is a member of theTNF-receptor superfamily. This receptor is activated by tumornecrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL),and thus transduces cell death signal and induces cell apoptosis.Studies with FADD-deficient mice suggested that FADD, a deathdomain containing adaptor protein, is required for the apoptosismediated by this protein. |
Immunogen | n/a |
Other Names | [Tumor necrosis factor receptor superfamily member 10A; Death receptor 4; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAIL-R1; CD261; TNFRSF10A; APO2; DR4; TRAILR1] |
Gene, Accession # | [TNFRSF10A], Gene ID: 8797, NCBI: NP_003835.3, UniProt: O00220 |
Catalog # | MBS9202890 |
Price | $165, $370 |
Order / More Info | TNFRSF10A (C-term), 418-446 Antibody from MYBIOSOURCE INC. |
Product Specific References | Shimada, M., et al. Hum. Genet. 128(4):433-441(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Wei, W., et al. Mol. Immunol. 47(15):2475-2484(2010) Park, S.W., et al. APMIS 118(8):615-616(2010) Tian, L., et al. J. Huazhong Univ. Sci. Technol. Med. Sci. 30(3):408-411(2010) |