Human AURORA-B KINASE Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human AURORA-B KINASE |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | bovine (expected from sequence), chimpanzee (expected from sequence), dog (expected from sequence), mouse (expected from sequence), porcine (expected from sequence), rat (expected from sequence) |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.05 mg |
| Concentration | IgG concentration 0.2mg/ml |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This item detects Aurora-B kinase (AurB), a serine/threonine kinase which is the enzymatic core of the Chromosomal Passenger Complex (CPC). This complex functions in chromosome alignment and separation, histone modification, and cytokinesis. CPC also includes three non-enzymatic subunits known as the inner centromere protein (INCENP), survivin, and borealin, which determine the activity, localisation, stability, and possibly even the substrate specificity of AurB.. . Two CPCs exist during mitosis- one containing all four members, and another consisting of INCENP and AurB. Quaternary CPC functions during chromosome alignment and cytokinesis, whereas the INCENP-AurB complex may be responsible for modifying histone H3.. . AurB is overexpre |
| Immunogen | Immunogen: Synthetic peptide corresponding to amino acids 227-238 of human Aurora-B kinase. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human Aurora-B kinase were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography. Target Species: Human |
| Other Names | [aurora kinase B isoform 2; Aurora kinase B; aurora kinase B; ARK-2; STK-1; aurora 1; aurora kinase B-Sv1; aurora kinase B-Sv2; aurora- and Ipl1-like midbody-associated protein 1; aurora-1; aurora-B; aurora-related kinase 2; aurora/IPL1-related kinase 2; protein phosphatase 1, regulatory subunit 48; serine/threonine kinase 12; serine/threonine-protein kinase 12; serine/threonine-protein kinase 5; serine/threonine-protein kinase aurora-B; aurora kinase B; Aurora 1; Aurora- and IPL1-like midbody-associated protein 1; AIM-1; Aurora/IPL1-related kinase 2; ARK-2; Aurora-related kinase 2; STK-1; Serine/threonine-protein kinase 12; Serine/threonine-protein kinase 5; Serine/threonine-protein kinase aurora-B], [AURKB; AURKB; AIK2; AIM1; ARK2; AurB; IPL1; STK5; AIM-1; STK12; PPP1R48; aurkb-sv1; aurkb-sv2; AIK2; AIM1; AIRK2; ARK2; STK1; STK12; STK5; AIM-1; ARK-2; Aurora-related kinase 2] |
| Gene, Accession # | Gene ID: 9212, NCBI: NP_001243763.1, UniProt: Q96GD4 |
| Catalog # | MBS221534 |
| Price | $375 |
| Order / More Info | Human AURORA-B KINASE Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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