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Antigenic Specificity | Calreticulin |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse, monkey |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Calreticulin antibody detects endogenous levels of total Calreticulin. Description: Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind |
Immunogen | Immunogen: Purified recombinant fragment of human Calreticulin expressed in E. Coli Subcellular Location: Endoplasmic Reticulum Lumen. Cytoplasm > Cytosol. Secreted > Extracellular Space > Extracellular Matrix. Cell Surface. Also found in cell surface (T cells), cytosol and extracellular matrix. Associated with the lytic granules in the cytolytic T-lymphocytes. |
Other Names | [Autoantigen RO; CALR; CALR protein; CALR_HUMAN; Calregulin; Calreticulin; cC1qR; CRP55; CRT; CRTC; Endoplasmic reticulum resident protein 60; Epididymis secretory sperm binding protein Li 99n; ERp60; FLJ26680; grp60; HACBP; HEL S 99n; RO; Sicca syndrome antigen A (autoantigen Ro; calreticulin); Sicca syndrome antigen A; SSA] |
Gene, Accession # | Gene ID: 811, NCBI: NP_004334.1, UniProt: P27797 |
Catalog # | MBS9602791 |
Price | $235, $295, $370 |
Order / More Info | Calreticulin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |