PELI2 - N-terminal region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PELI2 - N-terminal region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | cow, dog, guinea pig, horse, human, mouse, porcine, rabbit, rat, zebrafish |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This is a rabbit polyclonal antibody against PELI2. It was validated on Western BlotTarget Description: PELI2 is a E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. It is involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. It mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. It may be important for LPS- and IL1B-induced MAP3K7- dependent, but not MAP3K3-dependent, NF-kappa-B activation. And it can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1. |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PELI2 |
| Other Names | [E3 ubiquitin-protein ligase pellino homolog 2; E3 ubiquitin-protein ligase pellino homolog 2; E3 ubiquitin-protein ligase pellino homolog 2; pellino E3 ubiquitin protein ligase family member 2] |
| Gene, Accession # | [PELI2], Gene ID: 57161, NCBI: NP_067078.1, UniProt: Q9HAT8 |
| Catalog # | MBS3209212 |
| Price | $335 |
| Order / More Info | PELI2 - N-terminal region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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