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Antigenic Specificity | CD86 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal antibody to detect LAG3 in human and mouse samples. This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells; and it is the ligand for two proteins at the cell surface of T cells; CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described; but their full-length |
Immunogen | Immunogen: KLH conjugated synthetic peptide between 269-298 amino acids from the C-terminal region of human CD86. |
Other Names | [T-lymphocyte activation antigen CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B72; FUN-1; CD86; CD86; CD28LG2], [CD86; CD86; B70; B7-2; B7.2; LAB72; CD28LG2; CD28LG2] |
Gene, Accession # | [CD86], Gene ID: 942, NCBI: NP_001193853.1, UniProt: P42081 |
Catalog # | MBS845946 |
Price | $200 |
Order / More Info | CD86 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |