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Antigenic Specificity | Human Heparin Cofactor II |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1ug/ul |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody is specific for HCII as demonstrated by immunoelectrophoresis and ELISA. Heparin Cofactor II (HCII), also known as heparin cofactor A and dermatan sulphate cofactor, is a single chain glycoprotein produced in the liver and circulates in plasma at concentration of 50-100 ug/ml (0.8-1.5 uM). A member of the SERPIN family of proteinase inhibitors, HCII exhibits a relatively narrow specificity and is only known to inhibit the serine proteinases thrombin and chymotrypsin. The inhibitory activity toward thrombin is accelerated up to 1000-fold in the presence of optimal concentrations of heparin. Unlike Antithrombin, thrombin inhibition by HCII is also enhanced by dermatan sulphate. HCII has an apparent molecular weight of 65, 600 da |
Immunogen | Immunogen: Human Heparin Cofactor II purified from plasma. |
Other Names | [heparin cofactor II; heparin cofactor 2; serpin family D member 1] |
Gene, Accession # | Gene ID: 3053 |
Catalog # | MBS4157178 |
Price | $585 |
Order / More Info | Human Heparin Cofactor II Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |