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Antigenic Specificity | Phospho-RPS6KB1 (S418) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine, mouse, rabbit, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.35 |
Applications | Dot Blot (DB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This RPS6KB1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S418 of human RPS6KB1. This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been obser |
Immunogen | n/a |
Other Names | [Ribosomal protein S6 kinase beta-1; S6K-beta-1; S6K1; 70 kDa ribosomal protein S6 kinase 1; P70S6K1; p70-S6K 1; Ribosomal protein S6 kinase I; Serine/threonine-protein kinase 14A; p70 ribosomal S6 kinase alpha; p70 S6 kinase alpha; p70 S6K-alpha; p70 S6KA; RPS6KB1; STK14A] |
Gene, Accession # | [RPS6KB1], Gene ID: 6198, NCBI: NP_001258989.1, UniProt: P23443 |
Catalog # | MBS9204109 |
Price | $165, $370 |
Order / More Info | Phospho-RPS6KB1 (S418) Antibody from MYBIOSOURCE INC. |
Product Specific References | Adem, C., et al., Genes Chromosomes Cancer 41(1):1-11 (2004). Suzuki, Y., et al., Genome Res. 14(9):1711-1718 (2004). Gomez-Cambronero, J., et al., Leuk. Res. 28(7):755-762 (2004). Raught, B., et al., EMBO J. 23(8):1761-1769 (2004). Miyakawa, M., et al., Endocr. J. 50(1):77-83 (2003). |