LGR4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityLGR4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatProtein G purified
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC)
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DescriptionReceptor for R-spondins that potentiates the canonical Wnt signaling pathway and is involved in the formation of various organs. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Its function as activator of the Wnt signaling pathway is required for the development of various organs, including liver, kidney, intestine, bone, reproductive tract and eye. May also act as a receptor for norrin (NDP), such results however
ImmunogenImmunogen: Recombinant Human Leucine-rich repeat-containing G-protein coupled receptor 4 protein (234-365AA)
Other Names[Leucine-rich repeat-containing G-protein coupled receptor 4; G-protein coupled receptor 48; LGR4; GPR48]
Gene, Accession #[LGR4], Gene ID: 55366, NCBI: NP_001333361.1, UniProt: Q9BXB1
Catalog #MBS7106317
Price$160, $235
Order / More InfoLGR4 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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