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Antigenic Specificity | NKAP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: NKAP antibody detects endogenous levels of total NKAP. Function: Acts as a transcriptional repressor. Plays a role as a transcriptional corepressor of the Notch-mediated signaling required for T-cell development. Also involved in the TNF and IL-1 induced NF-kappa-B activation. Associates with chromatin at the Notch-regulated SKP2 promoter.Subunit Structure: Component of the Notch corepressor complex. Interacts with CIR1 and HDAC3.Similarity: Belongs to the NKAP family. |
Immunogen | Immunogen: A synthesized peptide derived from human NKAP (CKSPKPSKSARSPRG) Subcellular Location: Nucleus. Predicted Cross Reactivity: Rabbit Similarity: Rabbit (100%) |
Other Names | [NF-kappa-B-activating protein; NFKB activating protein; Nkap; NKAP_HUMAN; Nuclear NF kappaB activating protein] |
Gene, Accession # | [NKAP], Gene ID: 79576, NCBI: NP_078804.2, UniProt: Q8N5F7 |
Catalog # | MBS9609386 |
Price | $240, $280 |
Order / More Info | NKAP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |