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Antigenic Specificity | A20 Zinc Finger Protein |
Clone | [4H16] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1,k |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human A20 Zinc Finger Protein. NF-kB (nuclear factor kB) regulates the expression of a large number of genes that play critical roles in apoptosis, viral replication, tumorigenesis, various autoimmune diseases and inflammation. The zinc finger protein A20 is a tumor necrosis factor and interleukin 1 (IL-1)-inducible protein that negatively regulates NF-kB gene expression. A20 inhibits NF-kB dependent gene expression by interfering with a novel TNF-induced and RIP- or TRAF2-mediated pathway that is different from the NIK-IkB kinase pathway. A20 is expressed at low levels in most organs, the highest expression levels being in lymphoid tissues. |
Immunogen | Immunogen: Recombinant fusion protein of full length human A20 Zinc Finger Protein. Epitope: C-terminal portion of A20 (aa440-790). |
Other Names | n/a |
Gene, Accession # | NCBI: AGQ17407.1 |
Catalog # | MBS602153 |
Price | $600 |
Order / More Info | A20 Zinc Finger Protein Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |