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Antigenic Specificity | ROCK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, monkey, mouse, porcine, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | 0.57 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Affinity Purified Rho-associated protein kinase 1 Antibody. Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, PFN1 and PPP1R12A. Phosphorylates FHOD1 and acts synergistically with it to promote SRC-dependent non-apoptotic plasma membrane blebbing. Phosphorylates JIP3 and regulates the recruitment of JNK to JIP3 upon UVB-induced stress. |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region spanning 850-900 on human ROCK1 protein. Expression: Detected in blood platelets. |
Other Names | [coiled-coil-containing protein kinase 1; NY REN 35 antigen; p160 Rhoassociated coiled coil-forming protein kinase; p160 ROCK1; PRO0435; Renal carcinoma antigen NY REN 35; Rho associated coiled coil containing protein kinase 1; Rho-alpha kinase; Rho-associated protein kinase 1; Rok; rokalpha], [ROCK1; ROCK1; ROCK-I; P160ROCK; ROCK-I; p160ROCK] |
Gene, Accession # | [ROCK1], Gene ID: 6093, NCBI: Q13464.1, UniProt: Q13464 |
Catalog # | MBS540725 |
Price | $390 |
Order / More Info | ROCK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |