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Antigenic Specificity | NTRK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total NTRK2 antibody. The family of Trk receptor tyrosine kinases consists of TrkA, TrkB, and TrkC. While the sequence of these family members is highly conserved, they are activated by different neurotrophins: TrkA by NGF, TrkB by BDNF or NT4, and TrkC by NT3 (1). Neurotrophin signaling through these receptors regulates a number of physiological processes, such as cell survival, proliferation, neural development, and axon and dendrite growth and patterning (1). In the adult nervous system, the Trk receptors regulate synaptic strength and plasticity. TrkA regulates proliferation and is important for development and maturation of the nervous system (2). Phosphorylation at Tyr490 is required for Shc as |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human NTRK2. |
Other Names | [GP145-TrkB; TRKB] |
Gene, Accession # | [NTRK2], Gene ID: 4915, NCBI: NP_001007098.1, UniProt: Q16620 |
Catalog # | MBS9408547 |
Price | $255 |
Order / More Info | NTRK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |