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Antigenic Specificity | Synaptophysin |
Clone | [EP10] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Synaptophysin. This antibody recognizes human synaptophysin. Synaptophysin is a synaptic vesicle glycoprotein with four transmembrane domains. It is present in neuroendocrine cells and is a specific presynaptic marker for all neurons, neuroendocrine cells, and neoplasms of neuroendocrine origin. Synaptophysin plays a role in synaptic vesicle exocytosis including cholesteroldependent vesicle biogenesis, regulation of SNARE assembly via interaction with VAMP/synaptobrevin, formation of the fusion pore initiating neurotransmitter release, and activation of vesicle endocytosis. The gene for synaptophysin has been implicated in X-linked mental retardation. |
Immunogen | Antigen: Immunoprecipitate of human brain. |
Other Names | [synaptophysin; Synaptophysin; synaptophysin; OTTHUMP00000032504; OTTHUMP00000216753; OTTHUMP00000216756; major synaptic vesicle protein P38; synaptophysin; Major synaptic vesicle protein p38], [SYP; SYP; MRXSYP] |
Gene, Accession # | Gene ID: 6855, NCBI: NP_003170.1, UniProt: P08247 |
Catalog # | MBS190580 |
Price | $360 |
Order / More Info | Synaptophysin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |