LAR/PTPRF Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | LAR/PTPRF |
| Clone | [S165-38] |
| Host Species | Mouse |
| Reactive Species | human, rat, mouse |
| Isotype | IgG2a |
| Format | peroxidase (HRP) conjugate |
| Size | 0.1 mg |
| Concentration | 1mg/mL |
| Applications | Western Blot (WB), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background Info: Detects a 85 kDa protein (full length protein is 210 kDa - smaller due to proteolysis into P-subunit containing transmembrane and intracellular domains. Scientific Background: PTPRF or leukocyte common antigen-related protein (LAR) is a widely expressed protein tyrosine phosphatase with an extracellular receptor region that resembles a cell adhesion molecule. PTPRF removes phosphate group from beta-catenin, an event that may subsequently facilitate cell-cell adhesion and ensure the stability of the cadherin complex. This phosphatase has also been implicated in various cellular processes such as neurite growth, nerve regeneration, actin remodeling and regulation of insulin function (1,2,3,4). Anti-PTPRF (C-terminal) antibody |
| Immunogen | n/a |
| Other Names | [FLJ43335; FLJ45062; FLJ45567; LAR; LAR protein; LARFN5C; LARS; LCA homolog; Leukocyte antigen related (LAR) PTP receptor; Leukocyte antigen related; Leukocyte antigen related PTP receptor; Leukocyte antigen related tyrosine phosphatase], [PTPRF; PTPRF; LAR; BNAH2; LAR; LAR] |
| Gene, Accession # | Gene ID: 5792, NCBI: NP_002831.2, UniProt: P10586 |
| Catalog # | MBS800263 |
| Price | $425 |
| Order / More Info | LAR/PTPRF Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Streuli M. M., et al. (1992) EMBO Journal, 11(3), 897-907. 2. Mooney R.A. and C.M LeVea. (2003) Current Topics in Medicinal Chemistry, 3(7), 809-819. 3. Chagnon M.J., et al. (2004) Biochemistry and Cell Biology, 82(6), 664-675. 4. Ahmad F.F., and B.J. Goldstein (1997) Journal of Biological Chemistry, 272(1), 448-457. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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