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Antigenic Specificity | Cytokeratin 15 (KRT15) (Basal Cell Marker) |
Clone | [LHK15] |
Host Species | Mouse |
Reactive Species | human, rat, cow. |
Isotype | IgG2a, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma (BCC) and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differenti |
Immunogen | Immunogen: A 17 amino acids synthetic peptide from the C- terminal of Human Cytokeratin 15 Cellular Localization: Cytoplasmic |
Other Names | [CK15; Cytokeratin 15; K1CO; Ka15; Keratin 15 basic; Keratin 15 beta; Keratin complex 1 acidic gene 15; Keratin type I cytoskeletal 15; KRT15; KRTB; KRTL15; Type I cytoskeletal 15; Type I keratin Ka15] |
Gene, Accession # | [KRT15], Gene ID: 3866, NCBI: NP_002266.2, UniProt: P19012 |
Catalog # | MBS4380074 |
Price | $190, $340, $340 |
Order / More Info | Cytokeratin 15 (KRT15) (Basal Cell Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Inoue et al. 2009. Lab Invest. 89(8):844-56. Porter et al. 2000. Lab Invest. 80(11):1701-10. Waseem et al. 1999. J Invest Dermatol. 112(3):362-9. |